Please ensure Javascript is enabled for purposes of website accessibility Chemical Gloves - High Dexterity Work Gloves - RX Safety

Workers in laboratories, industrial cleaning, manufacturing, and agriculture routinely handle hazardous chemicals, and chemical-resistant gloves are one of the most important pieces of personal protective equipment (PPE) they wear to protect their hands.

That said, chemical protection is not a “one-size-fits-all” proposition. No single type of glove material protects you against all chemicals. The gloves you choose depend on the type of chemical you handle. Choosing the wrong glove material can put you at risk of chemical hand injuries, severe skin burns, or even systemic toxicity.

The most serious risk is silent failure, chemical permeation. Permeation occurs when chemical molecules move through glove material at a microscopic level without causing visible damage. Unlike degradation, the obvious and detectable physical breakdown of a glove, permeation doesn’t give a sign of its presence until the chemical has already contacted your skin.

Chemical-resistant gloves come in various barrier materials, including nitrile, neoprene, PVC, butyl rubber, and Viton. Each of these materials has a specific breakthrough time against different substances. Breakthrough time is the length of time a given chemical takes to permeate that material.

At RX-Safety, protecting you from harmful substances is our priority. Our gloves meet safety standards, such as ISO 374-1:2024 and ASTM F739-20, which measure the chemical resistance of protective gloves. We provide the data you need to compare the types of gloves to the Safety Data Sheet (SDS) of the specific chemical you’re using.

Don’t gamble with your skin safety. From heavy-duty acids to volatile solvents, find the exact barrier protection you need. Consult our chemical resistance charts, and browse our professional-grade glove selection below.

Frequently Asked Questions

To determine the appropriate glove material to use while working with a specific substance, check the chemical’s Safety Data Sheet (SDS), specifically Section 8 (Exposure Controls/Personal Protection). You should also match the chemical to a manufacturer’s chemical resistance chart and assess the material’s breakthrough time and permeation rate.

Breakthrough time is how long it takes for a chemical to permeate a protective barrier, like the material that makes up safety gloves, thereby indicating how long you can wear those particular gloves to work with that chemical before compromising your physical safety.

Some are reusable! Disposable gloves, such as nitrile or latex, should be discarded after a single use. You can clean, dry, and reuse gloves made from materials like neoprene, butyl, Viton, and PVC.

Chemical safety gloves often provide some resistance to punctures and cuts, but it depends on the material and thickness of the specific glove.

Flock-lined gloves feature an inner lining made of cotton fibers that absorb sweat and make the gloves easier to pull on and off. Unlined gloves do not have this lining and are typically single-use.

Many chemical gloves, particularly nitrile, latex, and neoprene, provide strong protection against biohazards and viruses, as long as they’re certified for both chemical and microbiological risks.

Viton gloves provide excellent protection against highly corrosive acids.

Store chemical-resistant gloves flat, in their original packaging, in a cool, dry, dark environment to avoid material degradation.

Category Highlights

Understanding Glove Ratings (Permeation vs. Degradation)

There are two ways that chemicals can get through your safety gloves and reach your skin: degradation and permeation.

Degradation is the physical deterioration of the glove material when it comes in contact with a chemical. Degradation causes visible damage, like swelling, melting, cracking, weakening, or becoming brittle.

Permeation is an invisible process that occurs at the molecular level when chemical molecules are able to break through the glove material’s barrier without causing visible physical changes.

At RX-Safety, our line of chemical-resistant safety gloves is rated by breakthrough time, a measurement that indicates the precise number of minutes for which you can safely work with a chemical before it reaches your skin.

We can’t overstate the importance of matching your glove’s performance rating to the exact concentration of the chemicals you’re working with.

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